Variance component linkage analysis indicates a QTL for femoral neck bone mineral density on chromosome 1p36
نویسندگان
چکیده
منابع مشابه
Variance component linkage analysis indicates a QTL for femoral neck bone mineral density on chromosome 1p36.
Osteoporosis is a common condition characterized by reduced skeletal strength and increased susceptibility to fracture. Eight million Americans over the age of 50 have osteoporosis of the femoral neck. The most important risk factor for osteoporosis is low bone mineral density (BMD), and several epidemiological studies have shown the importance of genetic factors in determining variability of B...
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BACKGROUND [corrected] By providing essential information regarding bone mineral density (BMD), Densitometry can predict the mechanical resistance of bone tissue and the risk of fractures. However, fractures frequently occur in the femoral cervix and the spine before the loss of BMD reaches the densitometric threshold of osteoporosis. MATERIAL AND METHODS We studied 46 patients with total hip...
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In contrast to conventional dual-energy X-ray absorptiometry, quantitative computed tomography separately measures trabecular and cortical volumetric bone mineral density (vBMD). Little is known about the genetic variants associated with trabecular and cortical vBMD in humans, although both may be important for determining bone strength and osteoporotic risk. In the current analysis, we tested ...
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BACKGROUND Many studies that analyzed bone mineral density (BMD) and skeletal factors of hip fractures were based on uncalibrated radiographs or dual-energy xray absorptiometry (DXA). QUESTIONS/PURPOSES Spatial accuracy in measuring BMD and morphologic features of the femur with DXA is limited. This study investigated differences in BMD and morphologic features of the femur between two types ...
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BACKGROUND Stress shielding of the proximal femur has been observed in a number of conventional cementless implants used in total hip arthroplasty. Short femoral-neck implants are claiming less interference with the biomechanics of the proximal femur. The goal of this study was to investigate the changes of bone-mineral density in the proximal femur and the clinical outcome after implantation o...
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ژورنال
عنوان ژورنال: Human Molecular Genetics
سال: 2001
ISSN: 1460-2083
DOI: 10.1093/hmg/10.21.2447